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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX16
All Species:
26.67
Human Site:
S246
Identified Species:
45.13
UniProt:
O14662
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14662
NP_001001433.1
325
37031
S246
E
I
R
Q
I
V
Q
S
I
S
D
L
N
E
I
Chimpanzee
Pan troglodytes
XP_514749
272
31071
E210
D
L
G
A
M
I
V
E
Q
G
T
V
L
D
R
Rhesus Macaque
Macaca mulatta
XP_001084615
321
36481
S242
E
I
R
Q
I
V
Q
S
I
S
D
L
N
E
I
Dog
Lupus familis
XP_853504
326
37253
S247
E
I
R
Q
I
V
Q
S
I
S
D
L
N
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVI5
326
37034
S247
E
I
R
Q
I
V
Q
S
I
S
D
L
N
E
I
Rat
Rattus norvegicus
O70257
261
29832
G200
G
M
M
I
H
E
Q
G
D
V
I
D
S
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511120
304
34831
E242
D
L
G
A
M
I
V
E
Q
G
T
L
L
D
R
Chicken
Gallus gallus
NP_001006295
326
37263
S247
E
I
R
Q
I
V
Q
S
I
S
D
L
N
E
I
Frog
Xenopus laevis
NP_001085029
304
35171
E242
E
L
A
G
M
V
V
E
Q
G
T
V
L
D
R
Zebra Danio
Brachydanio rerio
XP_691316
324
37513
S245
E
I
R
Q
I
V
Q
S
I
S
D
L
N
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
G230
A
M
L
V
E
S
Q
G
E
M
I
D
R
I
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16000
291
33234
M230
L
V
E
S
Q
G
E
M
V
D
R
I
E
Y
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SWH4
323
36414
S243
E
I
Q
Q
V
L
G
S
V
N
D
L
A
Q
I
Baker's Yeast
Sacchar. cerevisiae
Q08144
397
45857
G260
E
I
T
Q
L
A
R
G
V
L
E
V
S
T
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.3
97.2
95
N.A.
92.9
27.6
N.A.
82.4
88
78.1
78.7
N.A.
21.5
N.A.
21.5
N.A.
Protein Similarity:
100
83.6
98.1
96.9
N.A.
95.7
46.4
N.A.
88
95.4
88
90.4
N.A.
43
N.A.
41.8
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
6.6
N.A.
6.6
100
13.3
100
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
40
100
100
N.A.
100
20
N.A.
40
100
40
100
N.A.
13.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.6
22.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.9
43.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
15
0
8
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
0
0
0
0
0
8
8
50
15
0
22
0
% D
% Glu:
65
0
8
0
8
8
8
22
8
0
8
0
8
43
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
15
8
0
8
8
22
0
22
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
58
0
8
43
15
0
0
43
0
15
8
0
15
58
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
22
8
0
8
8
0
0
0
8
0
58
22
0
0
% L
% Met:
0
15
8
0
22
0
0
8
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
43
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
58
8
0
58
0
22
0
0
0
0
8
0
% Q
% Arg:
0
0
43
0
0
0
8
0
0
0
8
0
8
0
22
% R
% Ser:
0
0
0
8
0
8
0
50
0
43
0
0
15
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
22
0
0
8
0
% T
% Val:
0
8
0
8
8
50
22
0
22
8
0
22
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _